8:00

Registration opens

9:00-10:45

HALL: GRANDE 2

Early Career Investigators' pre-meeting

Chair: Kattri-Liis Eskla, University of Tartu, Estonia

9:00-9:45  David Eisner, University of Manchester, UK: Why is science not always reproducible: can we fix it?

9:55-10:45  Mathis Korseberg Stokke, University of Oslo, Norway: Keys to translational research

Tea/coffee

11:00-12:45

HALL: GRANDE 2

Early Career Investigators' pre-meeting

Panel discussion with Krista Rantanen (The Baker Company, US and The Francis Crick Institute, UK), Mathis Korseberg Stokke (University of Oslo, Norway), William E. Louch  (University of Oslo, Norway), and Nina Ullrich (Heidelberg University, Germany). 

Panel discussion includes 4 speakers, plus a chair. The speakers would have 10 min each to tell their career story, followed by the panel discussion. The keywords here would be how to start your lab; how to negotiate to get what you need; translating your research to the clinic, moving abroad to start your lab; differences between working in academia and industry.

Lunch

13:15-15:00

HALL: GRANDE 3

CARDIAC MUSCLE

Cardiac sodium homeostasis

Chair: Morten Bækgaard Thomsen, University of Copenhagen, Denmark

13:15-13:40  Davor Pavlovic, University of Birmingham, UK: Regulation of intracellular sodium in health and disease

13:40-14:05  Kirstine Calloe, University of Copenhagen, Denmark: The multifocal ectopic Purkinje-related premature contraction (MEPPC) syndrome and SCN5A variants

14:05-14:30  Carol Ann Remme, Amsterdam UMC, Netherlands: Trafficking and subcellular targeting of cardiac sodium channels: towards new therapeutic approaches

14:30-15:00 

Show-and-tell, ECR-s on the podium

13:15-15:00

HALL: ANDANTE

COMPARATIVE PHYSIOLOGY

The regulation and function of seasonal quiescent states in animals: a comparative approach

Organisers and chairs: David Hazlerigg, University of Tromsø, Norway

Sjannie Lefevre, University of Oslo, Norway

Rikke Birkedal, Tallinn University of Technology, Estonia

13:15-13:30 Welcome by the session organizers

13:30-14:00 Caroline Habold, Hubert Curien Multi-disciplinary Institute, CNRS, University of Strasbourg, France: Evolutionary Physiology of Mammalian Hibernation

14:00-14:30 Shona Wood, UiT – The Arctic University of Norway: Hibernation timing to reveal mechanisms of rheostasis

14:30-15:00 Étienne Lefai, Université Clermont Auvergne, France: The hibernation in brown bears: A model for medical and space research

13:15-15:00

HALL: GRANDE 2

SKELETAL MUSCLE

Exercise physiology - empowering muscle function beyond state-of-the-art....

13:15-13:25  Welcome by Johanna Lanner, Karolinska Institutet, Sweden

13:25- 14:05  Truls Raastad, Norwegian School Sport Sciences, Norway: Muscle quality and muscle mass – impact on force generating capacity and adaptations to training, ageing and immobilization

14:05-14:30  Tomas Venckunas, Lithuanian Sports University, Lithuania: Muscle (dis)adaptation with extreme ultrarunning

14:30-14:45  Niklas Joisten, TU Dortmund, Germany: Targeted metabolomics reveals elevated systemic levels of tryptophan metabolites during and after acute exercise

14:45-15:00  Arianna Mazzoli, University of Naples Federico II, Italy: Age-dependent skeletal muscle mitochondrial response to short-term increased dietary fructose

13:15-15:00

HALL: BOLERO 2

VASCULAR

Vascular SIG Pre-Meeting

Chairs: Charlotte Mehlin Sørensen and Joakim Armstrong Bastrup, University of Copenhagen, Denmark

13:15-14:00  Harry Struijker-Boudier, Maastricht University, The Netherlands: The role of microcirculation in hypertension in cancer patients

14:00 -14:20 Joakim Bastrup, University of Copenhagen, Denmark: The proteomic view of remodelling in hypertension: mesenteric vs cerebral arteries

14:20-14:40  Anders Kristensen, Aarhus University, Denmark: Endothelial cell remodelling in diabetes

14:40-15:00  Amy McDermott, University of Copenhagen, Denmark: Investigating the microvascular pathology of diabetic kidney disease using super resolution ultrasound scanning

13:15-15:00

HALL: GRANDE 1

NEUROSCIENCE

Neuronal plasticity in health and disease

Chair: Fabio Benfenati, University of Genova, Italy

13:15  Welcome by the organizers

13:15-13:45  Pietro Baldelli, University of Genova, Italy: A new master transcriptional regulator of homeostatic plasticity

13:45-14:15  Maria Lindskog, Uppsala University, Sweden: The synapse as the gearbox of the brain

14:15-14:45  Kattri-Liis Eskla, University of Tartu, Estonia: Hypothermia alleviates reductive stress, a novel and largely overlooked phenomenon at the root of ischemia reperfusion injury

14:45-15:00  ECR: Tuğçe Akgün, Marmara University School of Medicine, Turkey: MELATONIN PROTECTS AGAINST SEIZURE-INDUCED NEUROINFLAMMATION IN RATS BY A RECEPTOR-DEPENDENT MECHANISM

13:15-15:00

HALL: BOLERO 1

RENAL PHYSIOLOGY

Epithelial, Membrane Transport and Renal Physiology 

Chairs: Henrik Dimke, University of Southern Denmark, Denmark

Jenny Nyström, University of Gothenburg, Sweden

13:15-13:20  Welcome by Henrik Dimke and Jenny Nyström

SGLT2 Session (note session is 10+5)

13:20-13:35  Anja Billing, Aarhus University, Denmark: SGLT2 Inhibition Reveals Kidney Reconfiguration And Metabolic Inter-Organ Communication

13:35-13:50  Mia Jensen, University of Southern Denmark, Denmark: Sodium-Glucose Cotransporter 2 Inhibitor Dapagliflozin Attenuates Protein Abundance Of Collectin Kidney 1 In Diabetic Mice

13:50-14:05  Mathias Skov, Aarhus University, Denmark: The Sglt2 Inhibitor Empagliflozin Aggravate Urinary Tract Infection With Uropathogenic Escherichia Coli By A Glucose Independent Mechanism

14:05-14:15  Small break

Molecular Mechanisms Of Kidney Disease Session (note session is 10+5)

14:15-14:30  Falk Lichtenberger, Charité, Germany: Pharmaceutical Activation Of Soluble Guanylate Cyclase Reduces Acute Kidney Injury Progression To Chronic Kidney Disease

14:30:14:45  Vishalini Venkatesan, University of Copenhagen, Denmark: The Role Of Aquaporin 2 (AQP2) — Dependent Water Transport In Cyst Progression During Autosomal Dominant Polycystic Kidney Disease (ADPKD)

14:45-15:00  Maibritt Meldgaard Arildsen, Aarhus University, Denmark: Quantification Of Renal Cortical Microperfusion Using Non-Invasive Optical Imaging

15:00

Start of the walking tours at 15:00 (paid)

Tea/coffee

15:30-17:00

HALL: GRANDE 3

CARDIAC MUSCLE

EC coupling

Chair: William Louch, University of Oslo, Norway

15:30-15:55  Mathis Stokke, University of Oslo, Norway: CPVT - lessons learned from patients, mice and computational models

15:55-16:20  Nina Ullrich, Heidelberg University, Germany: Structural and functional maturation strategies to enhance EC coupling in hiPSC-cardiomyocytes

16:20-16:45  Grégoire Vandecasteele, Université Paris-Saclay, France: Role of the PKA type I in regulating cardiac contractility and heart failure development

16:45-17:00  Martin Laasmaa, Tallinn University of Technology, Estonia: Cardiomyocytes from female compared to male mice have larger ryanodine receptor clusters and higher calcium spark frequency

15:30-17:00

HALL: ANDANTE

COMPARATIVE PHYSIOLOGY

The regulation and function of seasonal quiescent states in animals: a comparative approach

15:30-16:00 Shannon Currie, Universität Hamburg, Germany: Colonizing the cold - torpor flexibility and novel conditions promote range shifts in hibernating bats

16:00-16:30 Jayme van Dalum, Department of Arctic and Marine Biology, UiT, Norway: Maternally programmed developmental diapause in voles

16:30-17:00 Philip Lehmann, Stockholm University, Sweden: Diapause transitions in a butterfly viewed through four “omic” lenses

17:00-17:15 Concluding remarks

15:30-17:00

HALL: GRANDE 2

SKELETAL MUSCLE

M for muscle, mitochondria, metabolism and muscle memory

15:30-16:00  Marta Murgia, Max Planck Institute, Germany: What happens to muscle mitochondria during spaceflight? A proteomic approach to inactivity and unloading

16:00-16:15  Romain Bernasconi, Tallinn University of Technology, Estonia: Creatine deficiency causes muscle-specific shift in the myosin heavy chain composition

16:15-16:30  Estela Santos Alves, Karolinska Institutet, Sweden: PGC1α1 attenuates mitochondrial dysfunction in mice with arthritis

16:30-16:45  Ferdinand von Walden, Karolinska University Hospital, Sweden: Mechanical loading alters skeletal muscle ribosomal rna 2´-o-methylation –demonstration of skeletal muscle ribosome specialization

16:45-17:15  Jean Farup, Aarhus University, Denmark: Spatial mapping of intercellular cross-talk in the skeletal muscle microenvironment

17:00  Concluding remarks → Mingle and network with drinks

15:30-17:00

HALL: BOLERO 2

VASCULAR

Vascular SIG Pre Meeting

15:30-16:15  Ulrike Muscha Steckelings, University of Southern Denmark, Denmark: Breaking the dogma: The good side of RAAS

16:15-16:35  Barbara Schreier, Julius-Bernstein Institute of Physiology, Martin Luther University Halle-Wittenberg, Germany: Epidermal growth factor receptor in smooth muscle cells increases obesity-induced vascular alterations and renal endorgan damage

16:35-16:55  Ask Carit Andersen, Aarhus University, Denmark: cRSC kinase potentiates the contractility of murine middle cerebral arteries independently of rho kinase

16:55-17:20  Flash talks: 3-minute talks (only 2 slides allowed), 1 minute for questions, 1 minute for speak exchange.

• Minze Xu, Charité – Universitätsmedizin Berlin, Germany: STIMULATION OF NO-SGC-CGMP SIGNALING PREVENTS VASOCONSTRICTION IN EX VIVO ACUTE KIDNEY INJURY MODEL

• Ines Drenjančević, University Josip Juraj Strossmayer Osijek, Croatia: HIGH SALT DIET SUPPRESSES NRF2-SIGNALLING PATHWAY AND IMPAIRS FLOW-MEDIATED DILATION IN MIDDLE CEREBRAL ARTERIES OF SPRAGUE-DAWLEY RATS

• Michał Kowara, Medical University of Warsaw, Poland: THE EXPRESSION LEVELS OF MIR-92A, AN ATHEROPROTECTIVE KLF2 DOWNREGULATOR AND MIR-126 – AN ATHEROPROTECTIVE MERTK DOWNREGULATOR CORRELATED WITH ATHEROSCLEROTIC LESIONS SEVERITY

15:30-17:00

HALL: GRANDE 1

NEUROSCIENCE

Neuronal plasticity in health and disease

Chair: Fabio Benfenati, University of Genova, Italy

15:30-16:00  Maria Ryazantseva, University of Helsinki, Finland: Chronic stress affects amygdala excitability by downregulation of kainate receptor subunit Gluk1

16:00-16:30  Sergiy V. Korol, Uppsala University, Sweden: GABA signaling in hippocampal DG granule cells is regulated by insulin, axis-location, age and is altered in the tg-APPSwe mouse model of Alzheimer’s disease

16:30-17:00  ECR: Carolin Kuuskmäe, University of Tartu, Estonia: KYNURENINE PATHWAY DYNAMICS IN PATIENTS WITH SCHIZOPHRENIA SPECTRUM DISORDERS ACROSS THE DISEASE TRAJECTORY

Concluding remarks

15:30-17:00

HALL: BOLERO 1

RENAL PHYSIOLOGY

Epithelial, Membrane Transport and Renal Physiology - a great opportunity for ECR to present their data

15:30-15:45  Luca Meoli, Charité - University Medicine Berlin, Germany: Phenotypic Characterization Of Cldn10b-Deficient Mice With A Focus On Kidney Function

Kidney Injury Session (note session is 10+5)

15:45-16:00  Aurelija Radzevičienė, Lithuanian University of Health Sciences, Lithuania: Relation Of Donor Kidney Injury Biomarkers With A 1-Year Allograft Function

16:00-16:15  Tobias Sieckmann, Charité - Charité - University Medicine Berlin, Germany: Dysregulation Of Renal Polyamine Levels After Kidney Injury

16:15-16:30  Barbora Kalocayova, Centre of Experimental Medicine, Slovak Academy of Sciences, Slovakia: Mitigation Of Cardiac Surgery-Associated Acute Kidney Injury: Administration Of Molecular Hydrogen

16:30-16:45  Marie Lykke Bach, University Of Southern Denmark, Denmark: The Urokinase Plasminogen Activator in the DOCA-salt Kidney Injury Murine Model Activates Complement Factor C3a

16:45-17:00 Aimi Hamilton, Aarhus University, Denmark: Uropathogenic Escherichia Coli Show Increased Motlity In Urine From Renal Transplant Recipients

17:30

Walking tour around Tallinn (free)

8:45-9:00

HALL: GRANDE

Opening ceremony
 

HALL: GRANDE

PLENARY

Chair: Susan Wray, University of Liverpool, United Kingdom

Ole Holger Petersen, Cardiff University, Wales, UK: Watching living cells in action in the pancreas

9:45-10:30

GROUP PHOTO (gathering at the registration area)

Tea/coffee
 

HALLS: DUETTO, FORTE, ALLEGRO, VALUUTA BAR AND LOBBY

Poster preview

10:30-12:15

HALL: GRANDE 3

SKELETAL MUSCLE SYMPOSIUM: NOVEL INSIGHT INTO SKELETAL MUSCLE PATHOPHYSIOLOGY IN DISEASE

Chair: Johanna Lanner, Karolinska Institutet, Sweden

10:30-11:00  Jorge Ruas, Karolinska Institutet, Sweden: Control of cell-cell communication during muscle remodeling and regeneration by a novel RNA-binding protein

11:00-11:20  ECR: Brendan Gabriel, The Rowett Institute, UK: Disrupted muscle circadian rhythms in metabolic disease – the importance of timing

11:20-11:40  Ferdinand von Walden, Karolinska University Hospital, Sweden: Skeletal muscle metabolism and exercise capacity in adolescents with cerebral palsy

11:40-12:10  Cristina Mammucari, University of Padova, Italy: Regulation of muscle metabolism and function by mitochondria cation channels 

10:30-12:15

HALL: GRANDE 1+2

SPS - HONORARY SYMPOSIUM: SODIUM AND FLUID BALANCE

Chairs: Helle Prætorius Øhrwald, Aarhus University, Denmark
Tobias Wang, Aarhus University, Denmark

10:30-10:50  Peter Bie, University of Southern Denmark, Denmark: Total body sodium: rates, pools, regulators, implications

10:50-11:10  Pernille B Laerkegaard Hansen, AstraZeneca and University of Southern Denmark, Denmark: From physiology to novel medicine and back

11:10-11:30  Peter Norsk, Baylor College of Medicine & Center for Space Medicine & NASA, JSC, United States: Mechanisms of diuresis and natriuresis of central blood volume expansion induced by head-out water immersion in humans

11:30-11:50  Boye L. Jensen, University of Southern Denmark, Denmark: Nephrogenic diabetes insipidus-therapeutic options

11:50-12:10  Pontus Persson, Charité Berlin, Germany: Intricate kidney circulation is key to understanding and treating kidney injury

10:30-12:15

HALL: BOLERO

ORAL ABSTRACTS: CARDIOVASCULAR PHYSIOLOGY

Chair: Christian Aalkjaer, Aarhus University, Denmark

10 minute presentation + 5 minutes Q&A

10:30-10:45  Rashika Sivakumar, Aarhus University, Denmark: THE ROLE OF SORTILLIN-RELATED VPS10P CONTAINING RECEPTOR, SORCS2 IN ENDOTHELIAL AND SMOOTH MUSCLE CELL FUNCTION

10:45-11:00  Lana Kralj, University of Ljubljana, Slovenia: SKIN MICROCIRCULATION RESPONSE TO GRADED DYNAMIC EXERCISE: A WAVELET ANALYSIS APPROACH

11:00-11:15  Lars Jørn Jensen, University of Copenhagen, Denmark: ROLE OF S1P-RECEPTOR AND Rho-KINASE IN MYOGENIC TONE IN MESENTERIC AND CEREBRAL ARTERIES OF YOUNG VS. MIDDLE-AGED MICE​

11:15-11:30  Joakim A Bastrup, University of Copenhagen, Denmark: ORAL DOSING HYPERTENSIVE RATS WITH ANTI-INFLAMMATORY AGENT COLCHICINE GIVES VASCULAR FUNCTION RECOVERY

11:30-11:45  Florencia Cabrera-Cabrera, Tallinn University of Technology, Estonia: DECIPHERING THE REGULATION OF NEUROTROPHIN BDNF GENE EXPRESSION IN CARDIOMYOCYTES

11:45-12:00  Ieva Sarapinienė, Lithuanian University of Health Sciences, Lithuania: PROTEIN KINASES AND CONNEXIN 43 C-TERMINUS RESIDUES INVOLVED IN ALLOSTERIC REGULATION OF GAP JUNCTION INHIBITOR POTENCY

12:00-12:15  Ornella Manfra, Oslo University Hospital and University of Oslo, Norway: SUPER-RESOLUTION IMAGING OF CARDIOMYOCYTE DYADIC PROTEINS​

12:15-14:15

AT MERINEITSI RESTAURANT

Lunch

HALLS: DUETTO, FORTE, ALLEGRO, VALUUTA BAR AND LOBBY

Poster session

HALL: GRANDE 1+2

KEYNOTE

Chair: Helle Prætorius Øhrwald, Aarhus University, Denmark

Lora Heisler, University of Aberdeen, UK: New insights in the brain control of obesity and type 2 diabetes

HALL: BOLERO

KEYNOTE

Chair: Eero Vasar, University of Tartu, Estonia

Mart Saarma, University of Helsinki, Finland: Novel regulators of cellular stress and neuronal survival

Tea/coffee

15:30-17:15

HALL: GRANDE 1+2

CARDIAC SYMPOSIUM: PHYSIOLOGY OF MITOCHONDRIA AND CARDIAC METABOLISM

Chairs: Morten Bækgaard Thomsen, University of Copenhagen, Denmark

Martin Laasmaa, Tallinn University of Technology, Estonia

15:30-15:55  Ellen Aasum, UiT The Arctic University of Norway, Norway: Obesity-induced alterations in cardiac metabolism and mechanoenergetics

15:55-16:20  György Hajnóczky, Thomas Jefferson University, USA: Tissue specific control of mitochondrial calcium uptake

16:20-16:45  Uwe Schlattner, University of Grenoble Alpes, France: AMP-activated protein kinase in murine heart: lessons learned from a cardiomyocyte-specific, inducible knock-down

16:45-17:00  ECR: Jelena Branovets, Tallinn University of Technology, Estonia: Calcium handling in creatine-deficient mouse hearts

17:00-17:15  ECR: Joona Valtonen, Tampere University, Finland: SLOW INACTIVATION OF CA2+ CHANNELS MANIFEST TO PROLONGATION OF ACTION POTENTIAL AND ARRHYTHMIAS IN HYPERTROPHIC CARDIOMYOPATHY

15:30-17:15

HALL: GRANDE 3

TEACHING SYMPOSIUM: CURRENT TRENDS IN TEACHING PHYSIOLOGY

Chairs: Margarethe Geiger, Medical University of Vienna, Austria

Jana Kivastik, University of Tartu, Estonia 

15:30-15:50 Liisa M. Peltonen, University of Helsinki, Finland: Some good airing needed

15:50-16:10 Stefano Gastaldello, Karolinska Institute, Sweden: Academia or not academia, this is the student’s problem

16:10-16:25 Britt Fuglesteg, University of Tromsø, Norway: Use of scratch tickets to activate medical students during repetition of basic muscle physiology

16:25-16:45 David Greensmith, University of Salford, UK: Enhancing student experience and graduate outcomes through inclusive physiology

16:45-17:05 ECR: Julius Juurmaa, East Tallinn Central Hospital, Tallinn University of Technology, Estonia: A structured, system-driven approach to practicing and teaching medicine

17:05-17:15 Questions/discussion

15:30-17:15

HALL: BOLERO

ORAL ABSTRACTS: NEUROBIOLOGY AND METABOLISM

Chair: Eero Vasar, University of Tartu, Estonia

10 minute presentation + 5 minutes Q&A

15:30-15:45  Serena Losacco, University of Genova, Italy: COMBINED ROLES OF A GONADAL-ADRENOCORTICAL LOOP AND A THALAMOCORTICAL LOOP IN A MODEL OF FIBROMYALGIA PATHOGENESIS

15:45-16:00  Meric Demeli Ertus, Turkey Zonguldak Bulent Ecevit University Medical Faculty, Turkey: MODULATION OF MOTOR ACTIVITY BY EPIGALLOCATECHIN GALLAT IN THE STEREOTAXIC RAT MODEL OF PARKINSON’S DISEASE​

16:00-16:15  Jaromir Myslivecek, Charles University, Czech Republic: BIOLOGICAL RHYTHMS OF MUSCARINIC RECEPTORS AND CHOLINESTERASES IN BRAIN AREAS INVOLVED IN MOTOR ACTIVITY CIRCADIAN RHYTHM​

16:15-16:30  Este Leidmaa, University of Tartu, Estonia; University of Bonn, Germany: ACUTE HIGH-FAT HIGH-SUGAR DIET RAPIDLY INCREASES BLOOD-BRAIN BARRIER PERMEABILITY IN MICE​

16:30-16:45  Naim Khan, Université de Bourgogne-France Comté (UBFC), France: FAT TASTE RECEPTOR AGONISTS DECREASE FAT-RICH FOOD INTAKE AND OBESITY IN OBESE MICE​

16:45-17:00  Linnéa Corell, Karolinska Institutet, Sweden: INDIVIDUALS WITH CEREBRAL PALSY HAVE AN ALTERED VENTILATORY RESPONSE TO ACUTE INCREMENTAL EXERCISE​

17:00-17:15  Fabiano Cimmino, University of Naples Federico II, Italy: OLEOYLETHANOLAMIDE IN THE TREATMENT OF OBESITY AND INSULIN RESISTANCE: MODULATION OF ENERGY BALANCE, MITOCHONDRIAL BIOENERGETICS AND GUT MICROBIOME​

Conference Dinner with the folk band Kiiora. Get a glimpse here (opens on the event's Facebook page)!
Buses leave Hotel Viru at 19:00, 19:15 and 19:20.

HALL: GRANDE

PLENARY

Chair: Professor Jens Leipziger, Aarhus University, Denmark

Jens Juul Holst,University of Copenhagen, Denmark: Future therapy of obesity and type 2 diabetes based on the physiological actions of a gut hormone

Presentation of the Christian Bohr Prize – The Scandinavian Physiological Society – Helle Prætorius Øhrwald – President

9:45-10:30

Tea/coffee

HALLS: DUETTO, FORTE, ALLEGRO, VALUUTA BAR AND LOBBY

Poster preview

10:30-12:15

HALL: GRANDE 1+2

NEUROSCIENCE SYMPOSIUM: NEURODEGENERATION

Chairs: Sergiy V. Korol, Uppsala University, Sweden

Maria Lindskog, Uppsala University, Sweden

10:30-11:00  Gilberto Fisone, Karolinska Institute, Sweden: Non-motor symptoms in Parkinson’s disease: Modelling sleep and circadian co-morbidities

11:00-11:30  Giorgio Grasselli, University of Genova, Italy: Structural and functional plasticity of cerebellar climbing fibers

11:30-11:50  ECR: Benjamin Portal, Uppsala University, Sweden: Early behavioral and synaptic changes in the APP NL-F mice model of Alzheimer’s disease

11:50-12:10  ECR: Katyayani Singh, University of Tartu, Estonia: Neuronal growth regulator 1 (NEGR1) cell adhesion molecules as connotation link between neuropsychiatric and neurodegenerative processes

10:30-12:15

HALL: GRANDE 3

RENAL SYMPOSIUM: THE DISEASED KIDNEY

Chairs: Henrik Dimke, University of Southern Denmark, Denmark

Jenny Nyström, University of Gothenburg, Sweden

10:30-11:00  Fredrik Palm, Uppsala University, Sweden: Oxygenation in the diseased kidney

11:00-11:30  Helle Prætorius Øhrwald, Aarhus University, Denmark: Impact of urosepsis and pyelonephritis on renal function (will be uploaded soon)

11:30-11:50  ECR: Kerstin Ebefors, University of Gothenburg, Sweden: The mesangium in diabetic nephropathy

11:50-12:10  ECR: Gitte Rye Hinrichs, University of Southern Denmark, Denmark: ENaC and Amiloride in nephrotic fluid and sodium retention

10:30-12:15

HALL: BOLERO

ORAL ABSTRACTS: MUSCLE PHYSIOLOGY

Chair: Rikke Birkedal, Tallinn University of Technology, Estonia

10 minute presentation + 5 minutes Q&A

10:30-10:45  Simona Kavaliauskiene, University of Oslo, Norway: FUNCTIONAL CONSEQUENCES OF TEMPERATURE-INDUCED CARDIOVASCULAR REMODELING IN FARMED ATLANTIC SALMON

10:45-11:00  Elisabetta Piva, University of Padova, Italy: INVESTIGATING THE INFLUENCE OF RISING SEAWATER TEMPERATURES ON FISH HEART: EXPLORING THE PHYSIOLOGICAL IMPACT OF CLIMATE CHANGE ON ANTARCTIC FISH

11:00-11:15  Emil Rindom, Aarhus University and Aarhus University Hospital, Denmark: GUT-DERIVED HUMORAL SIGNALING INDUCE RAPID POSTPRANDIAL MUSCLE GROWTH IN BURMESE PYTHONS​

11:15-11:30  Richie Goulding, Vrije Universiteit, Netherlands: ALTERED SKELETAL MUSCLE MITOCHONDRIAL MORPHOLOGY IN LATE MIDDLE-AGED HUMANS, DESPITE MAINTAINED MITOCHONDRIAL FUNCTION AND CONTENT

11:30-11:45  David Rizo-Roca, Karolinska Institute, Sweden: SARCOMERIC MITOCHONDRIAL CREATINE KINASE 2 MODULATES MITOCHONDRIAL HOMEOSTASIS AND IS DOWNREGULATED IN MEN WITH TYPE 2 DIABETES

11:45-12:00  Baptiste Jude, Karolinska Institutet, Sweden: CAN PGC-1Α1 COUNTERACT SKELETAL MUSCLE CAPILLARY RAREFACTION AND REDUCED GLUCOSE UPTAKE INDUCED BY CHRONIC INFLAMMATION?

12:00-12:15  Florian Britto, Institut Cochin, France: INFLUENCE OF MYOFIBER TYPOLOGY ON THE RESPONSE TO OVERLOAD-INDUCED SKELETAL MUSCLE HYPERTROPHY

12:15-14:15

AT MERINEITSI RESTAURANT

Lunch

HALLS: DUETTO, FORTE, ALLEGRO, VALUUTA BAR AND LOBBY

Poster session

HALL: GRANDE 1+2

KEYNOTE

Chair: Robert Zorec, University of Ljubljana, Slovenia

Agneta Nordberg, Karolinska Institutet, Stockholm, Sweden: Dynamic reactive astrogliosis in Alzheimer disease continuum

HALL: BOLERO

KEYNOTE

Chair: Liga Ozolina-Moll, University of Latvia, Latvia

Maija Dambrova, Riga Stradins University, Latvia: Acylcarnitines: Fatty Acid Energy Metabolites in Health and Disease

Tea/coffee

15:30-17:15

HALL: GRANDE 3

COMPARATIVE PHYSIOLOGY SYMPOSIUM: COMPARATIVE CARDIOVASCULAR PHYSIOLOGY

Organisers: Sjannie Lefevre, University of Oslo, Norway; Rikke Birkedal, Tallinn University of Technology, Estonia; Christian Aalkjær, Aarhus University, Denmark; Tobias Wang, Aarhus University, Denmark

Chair: Sjannie Lefevre, University of Oslo, Norway

Speakers:

15:30-15:55  Dunja Aksentijevic, Queen Mary University of London, Barts and the London Faculty of Medicine and Dentistry, William Harvey Research Institute, UK: Metabolic adaptations in non-model organisms yield cardiac pathophysiology insights

​15:55-16:20  John Mackrill, University College Cork, Ireland: Evolution of the cardiac dyad

16:20-16:45  Kirstine Callø, University of Copenhagen, Denmark: Electrical activation of the mammalian heart

16:45-17:10  Rikke Birkedal, Tallinn University of Technology, Estonia: Communication within cardiomyocytes

15:30-17:15

HALL: GRANDE 1+2

VASCULAR SYMPOSIUM: VASCULAR AUTOREGULATION IN SPECIAL TISSUES

Chairs: Charlotte Mehlin Sørensen and Joakim Armstrong Bastrup, University of Copenhagen, Denmark

15:30-15:55  Dirk-Jan Duncker, Erasmus Medical Centre, Netherlands (cardiac): Regulation of coronary blood flow during exercise

15:55-16:20  Ylva Hellsten, University of Copenhagen, Denmark: Regulation of skeletal muscle vascular tone in health and disease

16:20-16:45  Patrice Brassard, Université Laval, Canada (cerebral): Cerebral pressure-flow relationship: looking beyond the traditional view of cerebral autoregulation

16:45-17:10  Olga Sosnovtseva, University of Copenhagen, Denmark: Autoregulation-driven microcirculation of the kidney

15:30-17:15

HALL: BOLERO

ORAL ABSTRACTS: RENAL BIOLOGY AND METABOLISM

Chairs: Helle Praetorius, Aarhus University, Denmark and Pontus Persson, Charité, Germany

10 minute presentation + 5 minutes Q&A

15:30-15:45  Henrik Dimke, University of Southern Denmark and Odense University Hospital, Denmark: EXPOSURE OF JUNCTIONAL CLAUDIN-3 EPITOPES IN THE THICK ASCENDING LIMB OF CLDN19 DEFICIENT MICE

15:45-16:00  Timo Rieg, University of South Florida and James A. Haley Veterans Hospital, USA: ROLE OF RENAL NHE1 IN ACID-BASE REGULATION

16:00-16:15  Jens Leipziger, Aarhus University, Biomedicine, Denmark: ELEXACAFTOR/TEZACAFTOR/IVACAFTOR TREATMENT CORRECTS THE SALT-LOSING PHENOTYPE IN PEOPLE WITH CYSTIC FIBROSIS

16:15-16:30  Stephanie Franzén, Uppsala University, Sweden: VOLATILE ANESTHESIA HAS HIGHER ASSOCIATION WITH POSTOPERATIVE ACUTE KIDNEY INJURY AND INDEPENDENTLY IMPAIRS RENAL FUNCTION VIA RENAL SYMPATHETIC NERVE ACTIVITY​

16:30-16:45  Andraz Stozer, University of Maribor, Slovenia: CALCIUM OSCILLATIONS IN ISLETS OF LANGERHANS FROM CONTROL AND DIABETIC HUMANS: IMPLICATIONS FOR UNDERSTANDING NORMAL AND PATHOLOGICAL BETA CELL FUNCTION

16:45-17:00  Leyla Semiha Sen, Marmara University School of Medicine, Turkey: PHOENIXIN-14 ALLEVIATES REMOTE ORGAN INJURY IN BILE DUCT LIGATION INDUCED CHOLESTATIC LIVER INJURY AND ACUTE PANCREATITIS IN RATS​

17:00-17:15  Nalini Sodum, Oulu University Hospital, University of Oulu, Finland: L-CELLS NUTRIENT SENSING POTENTIATE GLP-1 RELEASE

17:15

HALL: GRANDE 1+2

Closing ceremony & awards